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People with chronic conditions, people of Indian background more vulnerable to COVID even after vaccine: UK study

A recent UK study found that people with chronic conditions such as Down syndrome, older people, men, as well as people of Pakistani and Indian backgrounds were more likely to end up in hospital or die after receiving both doses of the COVID vaccine. it occurs.

The Guardian reported that a team of researchers from the universities of Oxford, Edinburgh and Nottingham has developed a calculator to identify those at highest risk of contracting serious disease, despite being fully vaccinated. They examined hospital records of nearly 6.9 million fully and partially vaccinated adults, of whom 5.2 million had received both doses of the vaccine.

Based on this data, they found that the COVID vaccine did not provide the same level of protection against hospitalization and death for all groups. Some groups had a higher risk of falling seriously ill. The research found that people with Down syndrome had an almost 13-fold increased risk of death from covid compared to the rest of the population. The Guardian reports that there has been a nearly two-fold increase in people with dementia and Parkinson’s disease.

According to Aziz Shaikh, professor of primary care research and development at the University of Edinburgh and director of the Usher Institute, and a co-author of the paper, the increased exposure to the deadly virus may be due to increased exposure. The study found that in addition to older people, men and those from Indian and Pakistani backgrounds, people from disadvantaged backgrounds, the immunosuppressed, and those living in care homes also face a higher risk.

Sheikh said that some ethnic groups may be vulnerable to infection due to various social reasons. “I think the two subgroups that remain are speculative, but these groups – the Indians and the Pakistanis – tend to have a slightly higher domestic size and therefore may be of that sort within domestic broadcasting,” he told Sky News. .


They calculated the risk based on measures such as age, gender, ethnicity and background rate of COVID infection.

They suggest that their risk calculator could be useful for identifying sections of the population in the UK who would benefit from booster shots or early intervention – including the use of new treatments such as monoclonal antibodies, the BBC reported.

“The UK was the first place to implement a vaccination program and has some of the best clinical research data in the world. We developed this new tool using the QRSearch database,” said paper co-author Julia Hippiesley-Cox in a statement. to help the NHS identify which patients are at highest risk of serious outcomes despite vaccination for targeted interventions.”

The latest risk calculator is an updated version of a similar tool developed last year, using data from more than 6 million people to predict the outcome of COVID-19.

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