Young, healthy American woman has mild COVID. swelling of the brain after

New York: A team of US physicians has presented the first known case of a young, healthy adult who developed brain swelling after being infected with COVID-19, providing new insights into possible neurological effects after an infectious disease. provides.

Although COVID-19 is primarily thought of as a respiratory disease, patients often experience neurological problems such as headaches, anxiety, depression and cognitive issues, long after other symptoms have resolved. can remain.

Some research has linked blood vessel damage and inflammation in the brain and central nervous system (CNS) of COVID-19 patients referred to as vasculitis. Most cases of CNS vasculitis are associated with elderly patients with severe COVID-19.

In the journal Neurology: Neuroimmunology and Neuroinflammation, a multidisciplinary team of physicians at the University of California San Diego School of Medicine reported the case of a 26-year-old woman who was diagnosed with COVID-19 four days after an airplane flight in midair. was detected. March 2020.

Her symptoms were mild, but two to three weeks later she had difficulty moving her left leg and weakness on the left side of her body. He had no headache and did not notice any change in his mental state or cognition.

However, magnetic resonance imaging revealed multiple lesions in the right frontal region of the brain, which is involved in motor control and sensation on the left side of the body. A biopsy revealed CNS lymphocytic vasculitis – inflammation or swelling of the blood vessels in the brain and spine.

Jennifer Graves, a neurologist at UC San Diego Health, said, “This patient was the first confirmed case of COVID-19 CNS vasculitis, confirmed by biopsy, in an otherwise mild COVID-19 infection. in the young healthy patient.”

“His case calls on researchers and clinicians to consider these more serious potential brain complications, even in younger patients and those with mild initial COVID-19 infection,” she said.

The woman underwent a series of corticosteroid-based treatments, started a long-term immunosuppressant medication, and after six months, the lesions had significantly reduced and no new lesions had formed. Researchers said she is still being treated with immunosuppressive drugs.


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